English

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

Home > Products > Local Anesthetic Drugs > USP39 Standard Local Anesthetic Drugs Nature Pramoxine Hydrochloride / Pramoxine
 

USP39 Standard Local Anesthetic Drugs Nature Pramoxine Hydrochloride / Pramoxine

  • USP39 Standard Local Anesthetic Drugs Nature Pramoxine Hydrochloride / Pramoxine
Place of Origin:
HUBEI,CHINA
Brand Name:
HKYC
Certification:
IS09001
Model Number:

637-58-1

Min.Order Quantity:
10G
Price:
negotiable(bulk order enjoy discount)
Packaging Details:
designed disguied package according to different country, region and different quantity
Delivery Time:
within 24hours after payment confirm
Payment Terms:
T/T, D/P, Western Union, MoneyGram
Supply Ability:
1000kg per month
Contact Now
 

Product Description

USP39 Standard Local Anesthetic Drugs Nature Pramoxine Hydrochloride / Pramoxine HCl


1.Quick detail
Product name:Pramoxine Hydrochloride
Other name:Pramoxine Hcl
Pramoxine HCl CAS register number:637-58-1
Pramoxine HCl EINECS:211-293-1
Pramoxine HCl Molecular formula:C17H28ClNO3
Pramoxine HCl Molecular weight:329.86
Pramoxine HCl Assay:98.5%
Pramoxine HCl Appearance:White crystalline powder
Pramoxine HCl Usage:can be used as pharmaceutical material
2.Product Description:

Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride. During research and development,pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.
Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in man. Like other local anesthetics,paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.


3.Product Application:
The popular itch creams Gold Bond and some forms of Calamine Lotion use pramocaine hydrochloride to numb sensitive skin, as does the pain relief variant of Neosporin and some formulations of Sarna. The hydrochloride salt form of pramocaine is water-soluble.
Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations


Pramoxine hydrochloride COA


Items of analysis


Specification


Results

Description

White or off- white powder

Off- white powder

Solubility

Freely soluble in water and in alcohol ,soluble in chloroform,very slightly soluble in ether

complies

PH

About 4.5

4.45

IdentifIcation

IR,HPLC,IdentifIcation

Complies

Melting point

172.6ºC~173.5ºC

170ºC~174ºC

Loss on drying

≤1.0%

0.59%

Residue on ignition

≤0.1%

0.03%

Ethyl acetate

≤0.089%

Not detected

Ethanol

≤0.5%

0.06%

Petroleum ether

≤0.5%

0.02%

Triethylamine

≤0.5%

Not detected

Isopropanol

≤0.5%

Not detected

Assay

98.0%-102.0%

99.56%



USP39 Standard Local Anesthetic Drugs Nature Pramoxine Hydrochloride / Pramoxine Images

 

Send Inquiry

*Email

Please Enter your Email Address

Subject

Inquiry About

Quick question
Please select FAQ

I'm very interested in your products; could you send me some detail reference information?

Please send me detail product specification, thank you!

May I be an agency of your products,and what's yourterms?

We intend to purchase this product, would you please send me the quotation and minimum order quantity?

*Message
I want to buy

For the best results, we recommend including the following details: -Self introduction -Required specifications -Inquire about price/MOQ