Melanotan 2, Melanotan, Mt II, MT2
Melanotan 2 (MT2)Melanotan-II
Melanotan 2 CAS 121062-08-6
Melanotan 2 Purity (by HPLC): 99.00%
Melanotan 2 Appearance: White Powder
Melanotan 2 CAS Number: 121062-08-6
Melanotan 2 Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2
Melanotan 2 Molecular Formula: C50H69N15O9
Melanotan 2 Molecular weight: 1024.2
Storage Condition; away from light, cold storage (2-8 degree)
Usage: prevention sunlight-induce skin cancer; Sexual Dysfunction & Fat Decomposition
Melanotan II Description
Melanotan II is a peptide hormone belonging to the alpha-melanocyte-stimulating hormone (alpha-MSH) class of mimetics. Melanotan II is a synthetic analog pituitary derived Melanocortin. The peptide is primarily known for its ability to help with tanning but is also used to aid in erectile function. Melanotan II, also referred to as MT-2, has no use of significance beyond tanning and erectile function.
Melanotan II Effects
The effects of Melanotan two revolve around nothing more than tanning and possible erectile dysfunction relief. A darker and deeper tan may be noticed in a few days (assuming one is also tanning) and should produce notable results in a few weeks. The longer one uses MT-2 the darker he will get.
The effects of Melanotan II on erectile dysfunction take approximately 4-6 hours to take effect and should last 6-12 hours depending on individual response. Timing is important if used for this purpose. However, there are those that run small daily to every other day doses in order to provide a maintenance relief, but this can prove problematic to the skin if not careful.
Melanotan II Dosage
Melanotan II is provided in freeze-dried (lyophilized) form and reconstituted with bacteriostatic water. MT-2 may be injected subcutaneously or intramuscularly with subcutaneous being the most common and convenient. Melanotan II should be kept refrigerated at all times, and should be discarded in 30 days after reconstitution.
Melanotan II is typically taken at a dose of 0.5-2mg per day with 0.5-1mg being enough for most individuals who use it for tanning purposes. The same 0.5-1mg dosing is sufficient for erectile dysfunction treatment.
How to use Melanotan 2 Mixing the solution
Flip off the cap from the Melanotan 2 Tanning Injection vial.
Wipe the surface of the top of the vial with the enclosed alcohol wipe and discard the wipe.
Wipe the surface of the injectable water tube (or glass water vial depending on the pack ordered) with the enclosed alcohol wipe and discard the wipe.
Remove the enclosed syringe from the packaging. Making sure the injectable water tube is upright, insert the needle of the syringe into the sidewall of the water.
Now pull back the plunger of the syringe so you withdraw 1ml of water and slowly pull the syringe out.
Insert the syringe into the Melanotan 2 Tanning Injection vial and depress the plunger so you completely empty the syringe of the water and slowly remove the syringe from the vial. Do not shake the solution.
Place the Melanotan 2 solution in the fridge for storage until ready for use.
Make sure you put the syringe caps on and carefully dispose of it.
You have now mixed your Melanotan 2 Tanning Injection solution. Please store the solution in the fridge.
How to use Melanotan II for tanning
Melanotan II is typically provided in vials containing 10 mg of lyophilized (freeze-dried) powder. The vials are reconstituted with a convenient amount of bacteriostatic or sterile water, added to the vial by syringe. An example convenient amount of water is 2.5 mL. When this amount of water is used, the resulting solution contains 4 mg of MT-II per mL. If for example wishing to take a dose of 1 mg, a volume of 0.25 mL, or "25 IU" as marked on an insulin syringe, would be taken by injection. Injection may be subcutaneous, intramuscular, or intravenous, according to personal preference.
Injection typically is only once per day, but where a person is first trying the drug and judging tolerance, injection may be divided into two smaller amounts per day.
Typical dosage range is 0.5 to 2.0 mg/day, with a preferred range of 0.5 to 1.0 mg/day. However, its best to first assess tolerance with lower dosing of 0.25 mg at a time.
After reconstitution, a Melanotan II vial should preferably be consumed entirely within 30 days. Prior to reconstitution, MT-II should be stored in the refrigerator or freezer, but its acceptable for it to be shipped without refrigeration.
Use generally should be discontinued if MT-II, in the individual case, causes problems with increased growth, number, or darkness of moles.
Melanotan IIs effect is fairly long-lasting. It can even be the case that it takes a year or more for a cycles effect to largely disappear. Use of maintenance cycles can maintain effect indefinitely. As a rule of thumb, maintenance typically requires about 2 to 3 times as much MT-II per year as was needed for the first cycle. This can be taken either as a total of 2 to 3 cycles per year done in the same way as the initial cycle, or any more frequent dosing pattern providing this total amount of MT-II per year
What is Melanotan 2 ?
Melanotan 2 Tanning Injections (otherwise known as MT2) was first synthesized at the University of Arizona. Researches there knew that onc of the best defenses against skin cancer was melanin activated in the skin, a tan. They hypothesized that an effective way to reduce skin cancer rates in people would be to induce the bodys natural pigmentary system to produce a protective tan prior to UV exposure. The bodys naturally occuring hormone MSH causes melanogenesis, a process by which the skins pigment cells (melanocytes) produce the skins pigment (melanin). They tested to see if administering this endogenous hormone to the body directly could be an effective method to cause sunless tanning. What they found was that while it appeared to work, natural MSH had too short a half life in the body to be practical as a therapeutic drug. So they decided to find a more potent and stable alternative, one that would be more practical.
After synthesizing and screening hundreds of molecules, the researchers headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7] MSH, that was approimately 1,000 times more potent than the natural MSH. They dubbed this new peptide molecule, "Melanotan" (later Melanotan-1, now know as afamelanotide). They subsequently developed another analog, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2), which they called "Melanotan" Tanning Injections. The scientists hoped to use these peptides to combat melanoma by stimulating the bodys natural pigmentary mechanism to create a tan without first needing exposure to harmful levels of UV radiation. This in turn, they hypothesized, could reduce the potential for skin damage that can eventually lead to skin cancer.
A pilot phase I clinical trial conducted on three males by the College of Medacine, Pharmacology Department, University of Arizona in Tuscon, Arizona pulished in 1996 reported that, "Melanotan" Tanning Injections has tanning activity in humans given only 5 low doses every other day by subcutaneous injection." The side effects reported were mild nausea and a "stretching and yawning complex" that correlated with spontaneous penile erections.
The Department of Pharmacology, University of Arizona College of Medacin published in 1998 that involved 10 men who suffered from psychogenic erectile dysfunction. Their trial concluded that, "Melanotan" Tanning Injections is a potent initiator of erections in men with pyschogenic erectile dydfunction and has manageable side effects at a dose of 0.025mg/kg.
A clinical study published in 2000 of 20 men with psychogenic and organic erectile dysfunction conducted at the Section of Urology of The University of Arizona College of Medacin concluded, "that Melanotan II Tanning Injections is a potent initiator of penile erection in men with ecrectile dysfunction.
Melanotan II benefits
Lasting Tan:Even if dosage is stopped, a warm sun-kissed tan can last for months at a time without any exposure to the sun.Conversely, tans developed naturally fade in around a months time.
Flexibility of Use:Able to take a small loading dose with continued dosing until desired skin pigmentation is achieved.Once achieved only need to dose once every couple of weeks to maintain same pigment.
Reduced exposure to sunlight (UV rays):Melanotan still needs exposure to sunlight to be effective.However it will allow the user a significant reduction in time to develop desired tan .
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