98.5%High Quality Peptides Elcatonin For Hypercalcaemia Effection CAS 60731-46-6
Synonyms: 17-Dicarbcalcitonin (salmon), 1-butanoic acid-26-L-as partic acid-27-L-valine-29-L-alanine
EINECS NO: 262-393-7
Molecular Formula: C148H244N42O47
Molecular Weight: 3363.78 g/mol
Purity (HPLC): 98%min
Grade: Pharmaceutical grade
Storage: Reconstitute in ddH2O. Store at -20°C. Product is stable for at least 12 months
Packaging: Plastic vial (dedicated for peptide packing) or glass vial, quantity according to customers detail requirement. Usually 2mg*10vials/kit
Appearance: Sterile Filtered White lyophilized (freeze-dried) powder
Minimum Order Quantity: 1 mg
Usage: ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Human Secretin stimulates the secretion of bicarbonate by the pancreas and inhibits the production of gastrin and acid production in the stomach. It also potentiates the release of digestive enzymes from the pancreas triggered by cholecystokinin
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Elcatonin is a Calcitonin derivative which is transformed from eels calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Water Content(Karl Fischer) :≤10.0%
Acetate Content(by HPLC) :≤15.0%
Amino Acid Composition :±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N) :≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins :≤5EU/mg
Indications: Hypercalcaemia, paget`s disease of bone, osteoporosis, reflex sympathetic dystrophy
It is used in the treatment of diseases characterised by high bone turnover such as Paget’s disease of bone. They are also given as an adjunct in the treatment of severe hypercalcaemia, especially that associated with malignancy. Some calcitonins are used in the management of osteoporosis.
||1,7-Dicarbacalcitonin (salmon), 1-butanoic acid-26-L-aspartic acid-27-L-valine-29-L-alanine
|Amino Acid Composition
||Biological Activity (based on net peptide) was found to be 6695.2 IU/mg.
Purity by HPLC
Greater than 93.3% as determined by:(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
|Purity by SDS-PAGE
||Centrifuge the vial prior to opening. Reconstitute in sterile dW to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 2-7 days and at -20 °C for future use
Lyophilized Elcatonin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Elcatonin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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Elcatonin Peptides Steroids For Hypercalcaemia Effection CAS 60731 Images