98% Purity Beta-Amyloid (1-42) Human for Pathology of Alzheimer CAS 107761-42-2
Quick Detail :
Product Name: Beta-Amyloid (1-42), Ultra Pure, HFIP
Molecular Mass: 4514.1 4
Counter Ion:HFIP treated
Supplied As: No salt, as HFIP desalts the sample.
Recombinant. A DNA sequence encoding the human beta-amyloid (1-42)sequence was expressed in E. coli.
Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD)1-3. AD is the most common neurodegenerative disease and afflicts about 10% of the population over 60 4. The abeta,HFIP is described in Stine, et. al.3.
1) Yankner, BA, et. al., (1990) Science, 250: 279-282
2) Selkoe, D.J., (2001) Physiol. Rev, 81: 741-766
3) Stine, W.B. et. al., (2003) J. Biol. Chem, 278: 11612-11622
4) Frank, R.A., et. al., (2003) Neurobiology of Aging, 24: 521-536
Product Name: Beta-Amyloid(1-42), HFIP
Column: 4.6*250mm, SP-300-5-C4-BIO
Solvent A: 0.1%Trifluoroacetic in 100% Acetonirile
Solvent B: 0.1%Trifluoroacetic in 100% Water
Flow rate: 1.0ml/min
This product is a chemically-modified β-amyloid (1-42) precursor, which belongs to GenScript’s click peptides. The click peptides; are best described by the following key features:
1. Enhanced Stability—The O-acyl moiety within the click peptide is stable even under acidic pH.
2. Convenient and quick process—The click peptides can be easily converted to native peptide at pH 7.4 or above.
3. No by-product formation in the conversion process.
4. Superior quality—After the click, the aggregative property of the peptides is significantly minimized compared to its native format
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1. 2 mg / vial or specific packing required by customer
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98% Purity Beta-Amyloid (1-42) Human for Pathology of Alzheimer CAS 10 white Images