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HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

Home > Products > Peptides Steroids > Peptides Powder Pentadecapeptide BPC 157 [2mg] Therapy Of Inflammatory Bowel
 

Peptides Powder Pentadecapeptide BPC 157 [2mg] Therapy Of Inflammatory Bowel

  • Peptides Powder Pentadecapeptide BPC 157 [2mg] Therapy Of Inflammatory Bowel
Place of Origin:
China
Brand Name:
HBYC
Certification:
ISO 9000, SGS
Model Number:

HBYC

Min.Order Quantity:
10vials
Price:
negotiable(best offer will be provided)
Packaging Details:
designed disguised packing ways, 100% pass custom guarantee)
Delivery Time:
within 24hours after payment confirm
Payment Terms:
T/T, Western Union, MoneyGram,Bitcoin
Supply Ability:
1000Kg per Month
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Product Description

Peptides Powder Pentadecapeptide BPC 157 [2mg] Therapy Of Inflammatory Bowel Disease (IBD) CAS NO.137525-51-0

 

 

 

Product Name :Pentadecapeptide Bpc 157
CAS NO.137525-51-0
MF :C62H98N16O22
MW:1419.53552
EINECS Number:212-729-3
Purity: 99.50%
Apprarance:White Lyophilized Powder
Specification:2mg/vial
Grade: Pharmaceutical Grade
Storage:Lyophilized peptides although stable at room temperature for 3 months, should, be stored
desiccated below -18° C.
Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18°


Description

Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants. Cell proliferation of cultured tendon fibroblasts derived from rat Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay. However, the survival of BPC 157-treated cells was significantly increased under the H(2)O(2) stress.


Abstract
Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants. Cell proliferation of cultured tendon fibroblasts derived from rat Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay. However, the survival of BPC 157-treated cells was significantly increased under the H2O2 stress. BPC 157 markedly increased the in vitro migration of tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes. The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered. In conclusion, BPC 157 promotes the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway.

 

Applications

Stable gastric pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, M.W. 1419) may be the new drug stable in human gastric juice, effective both in the upper and lower GI tract, and free of side effects. BPC 157, in addition to an antiulcer effect efficient in therapy of inflammatory bowel disease (IBD) (PL 14736) so far only tested in clinical phase II, has a very safe profile, and exhibited a particular wound healing effect. It also has shown to interact with the NO-saystem, providing endothelium protection and angiogenic effect, even in severely impaired conditions (i.e., it stimulated expression of early growth response 1 gene responsible for cytokine and factor generation and early extracellular matrix (collagen) formation (but also its repressor nerve factor 1- A binding protein-2)), important to counteract severe complications of advanced and poorly controlled IBD.

 

Dosages

Experiments saw results with oral, peritoneal, and site injections. 10 micrograms per kg was the dose in rats for these results. This means oral or injection makes no difference, with a tiny bit of this healing becomes a whole lot easier.

 

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6. The most important thing is that we have resend policy to protect you 100%.

 

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We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.


Payment & Shipping Terms:


Minimum Order Quantity:100vials
Price:Negotiable
Packing:vials or as required
Delivery Time: within 24hours after receiving full payment.
Payment terms:T/T,Western Union,MoneyGram.

 

 

How to proceed an order:
1st: Please let me know what you need-Which product/Cas No. quantity, and the destination country.
2nd: You send us the purchase order once we cme to an agreement on all details.
3rd: Parcel would be delivered upon full payment received.
4th: Express Tracking No.will be provided about the parcels.
5th: You will get the parcels in 7days.
6th: After-sales service would be provided after you receive parcels.

Should you have any inquires please feel free to contact me ,kathelin(at) yccreate(doc)com.

 

 

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Nootropic Raw Powders
No. Name Cas no.
1 Sunifiram CAS: 314728-85-3
2 Pirespa CAS: 53179-13-8
3 Adrafinils CAS: 63547-13-7
4 Coluracetam CAS: 135463-81-9
5 Noopept CAS: 157115-85-0
6 Piracetam CAS:7491-74-9
7 Idebenone CAS:58186-27-9
8 Carphedon CAS:77472-70-9
9 Pramiracetam CAS:68497-62-1
10 Rivastigmine CAS:123441-03-2
11 Oxiracetam CAS:62613-82-5
12 Aniracetam CAS:72432-10-1
13 Donepezil CAS:120014-06-4
14 Rivastigmine tartrate CAS:129101-54-8
15 Alpha GPC CAS:28319-77-9
16 CRL-40,941(Fladrafinil) CAS:90212-80-9
17 Fasoracetam CAS:110958-19-5
18 Galantamine CAS:1953-04-4
19 9-fluorenol CAS:1689-64-1
20 NSI-189 free base CAS:1270138-40-3
21 NSI-189 phosphate CAS:1270138-41-4
22 Phenibut CAS:1078-21-3
23 Picamilon CAS:62936-56-5
24 PRL-8-53 CAS:51352-87-5
25 Tianeptine sodium CAS:30123-17-2
26 Vinpocetine CAS:42971-09-5
27 Vincamine CAS:1617-90-9
28 Theacrine CAS:2309-49-1
29 Unifiram CAS: 272786-64-8
30 CDP Citicoline CAS:987-78-0
31 Huperzine A CAS:102518-79-6
32 brivaracetam CAS:357336-20-0
33 Etiracetam CAS:33996-58-6
34 Raubasine CAS:483-04-5
35 Entacapone CAS:130929-57-6

 

Sleep Aid CAS NO.
Melatonine 73-31-4
Phenibut 1078-21-3
Suvorexant(MK-4305) 1030377-33-3
Agomelatine 138112-76-2
Trazodone HCL 25332-39-2
Sertraline HCL 79559-97-0
gamma-Oryzanol 11042-64-1
Trifluoperazine dihydrochloride 440-17-5
Sulpiride 15676-16-1
Levosulpiride 23672-07-3
Chloral hydrate 302-17-0
Tianeptine Sodium 30123-17-2
NSI-189 1270138-40-3
NSI-189 Phosphate 1270138-41-4
Tianeptine 66981-73-5
Tianeptine Sulfate 1224690-84-9
5-HTP 56-69-9
Escitalopram Oxalate 219861-08-2

 

 

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Nolvadex 20mg/ml oral  
Letrozole 5mg/ml(oral) -----------TBC
Anastrozole 5 mg/ml (oral)  

 


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