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HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

Home > Products > Pharmaceutical Raw Materials > Pharmaceutical Raw Materials Non Sedative Antihistamine Levocetirizine
 

Pharmaceutical Raw Materials Non Sedative Antihistamine Levocetirizine

Place of Origin:
China
Brand Name:
GONGCHUANG
Certification:
ISO9001,USP,KOSHER,etc
Model Number:

SARM

Min.Order Quantity:
10gram
Price:
negotiable
Packaging Details:
25k/Drum
Delivery Time:
arrange package within 2working days after payment
Payment Terms:
T/T, Western Union, MoneyGram,bitcoin
Supply Ability:
500kg+ each week
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Product Description

Pharmaceutical Raw Materials Non Sedative Antihistamine Levocetirizine Dihydrochloride

 

Levocetirizine dihydrochloride English name: Levocetirizine dihydrochloride
Levocetirizine dihydrochloride (2-4-chlorophenyl) phenylmethyl] -1-piperazinyl] ethoxy] -acetic acid dihydrochloride; LevocetrizineHCl; LEVOCETIRIZINE; LEVOCITIRIZINE DIHYDROCHLORIDE
Levocetirizine dihydrochloride CAS No.: 130018-87-0
Levocetirizine dihydrochloride Molecular formula: C21H27Cl3N2O3
Levocetirizine dihydrochloride Molecular weight: 461.81
Levocetirizine dihydrochloride EINECS number: 200-659-6


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COA:


Product Name

Levocetirizine HCL

CAS No.:

130018-87-0

Content:

≥ 99.00%

Appearance:

A white,Crystalline Powder or colorless crystals

Formula:

C21H27Cl3N2O3

Molecular Weight

461.81

Moisture:

≤0.1%

Loss on Drying:

≤0.2%

Residue on ignition:

≤0.1%

Heavy Metals:

≤10PPM

Acidity or Alkalinity:

Conform

Chloride:

Conform

Readily Carbonizable Substances:

Conform

Ordinary Impurities:

Conform
 

Basic Info

Product name Levocetirizine Dihydrochloride
CAS No. 130018-87-0
EINECS No. 200-659-6
M.F. C21H27Cl3N2O3
M.W. 461.81
Appearance White powder


Description
Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group.It is the S-enantiomer of bupivacaine.

The hydrochloride salt of levobupivacaine,an amide derivative with anesthetic property.Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane),thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine,levobupivacaine is associated with less vasodilation and has a longer duration of action.

 

Quick View:
Levocetirizine (as levocetirizine dihydrochloride) is a third-generation non-sedative antihistamine, developed from the second-generation antihistamine cetirizine. Chemically, levocetirizine is the active enantiomer of cetirizine. It is the R-enantiomer of the cetirizine racemate. Levocetirizine works by blocking histamine receptors. It does not prevent the actual release of histamine from mast cells, but prevents it binding to its receptors. This in turn prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief from the typical symptoms of hay fever.

3. History and formulations:
(1) Levocetirizine was first launched in 2001 by Belgian pharmaceutical company UCB. It is sold under the brand name Xyzal in Australia, Austria, Croatia, Czech Republic, Finland, France, Ireland, Lithuania, Netherlands, Portugal, Romania, Taiwan, Turkey, The Philippines, United States, Serbia, Slovakia, Slovenia, South Africa and UK; Xuzal in Mexico; Xusal in Germany; Xazal in Spain; And Xozal in Greece. In Hungary it is marketed by Richter Gedeon under the Zilola brand name.
(2) In India, levocetirizine is marketed by GlaxoSmithKline and UCB under the brand name Vozet and Xyzal Respectively. On May 25, 2007, the United States Food and Drug Administration approved Xyzal, where it is co-marketed by Sanofi-Aventis. Torrent Pharma launched UVNIL in rural market of India. It is also available as LEZYNCET 5 mg tablets through Unichem in India. In India, generic name of Lev-Cit 5 mg is manufactured by VIP Pharmaceuticals. Also marketed in India by Croslands (Ranbaxy Laboratories Ltd. ) under the brand name Teczine. In Brazil it is marketed under the brand name yxem by Farmalab. It is marketed in Egypt by BORG Pharma under the brand name Xaltec, Allear by western pharmaceuticals and levcet by marcryl.
(3) In Pakistan levocetirizine was first launched in liquid formulation by Novartis Consumer Health Division by the name of T-Day Syrup. It is available as 5 mg-strength tablets and a 0.5 mg/mL oral solution. In Pakistan levocetirizine is available in liquid formulation as well with the name of OCITRA and T-Day 2.5 mg/5 mL. In Bangladesh levocetirizine is available in 5 mg tablet & 2.5 mg/5 mL oral liquid formulation with the brand name of Alcet marketed by Healthcare Pharmaceuticals and Seasonix marketed by Incepta Pharmaceuticals. In Nepal levocetirizine is available in 5 mg tablet with brand name of Curin manufactured by Beximco Pharma.
Pain Killer Local Anesthetic APIS Levobupivacaine Hydrochloride 27262-48-2

What is the Levobupivacaine Hydrochloride ?
Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.
The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.


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Pharmaceutical Raw Materials Non Sedative Antihistamine Levocetirizine Images

 

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