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HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

Home > Products > Pharmaceutical Raw Materials > Pharmaceutical Raw Materials Anti-Cancer Doxorubicin Hydrochloride Powder CAS:
 

Pharmaceutical Raw Materials Anti-Cancer Doxorubicin Hydrochloride Powder CAS:

Place of Origin:
China
Brand Name:
GONGCHUANG
Certification:
ISO9001,USP,KOSHER,etc
Model Number:

SARM

Min.Order Quantity:
10gram
Price:
negotiable
Packaging Details:
25k/Drum
Delivery Time:
arrange package within 2working days after payment
Payment Terms:
T/T, Western Union, MoneyGram,bitcoin
Supply Ability:
500kg+ each week
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Product Description

Pharmaceutical Raw Materials Anti-Cancer Doxorubicin Hydrochloride Powder CAS: 25316-40-9

Top Quality 99% CAS 25316-40-9 Doxorubicin hydrochloride/Doxorubicin Hcl

 

Doxorubicin Hcl Product Name:Doxorubicin hydrochloride
Doxorubicin Hcl Alias:Adriamycin,
Doxorubicin Hcl CAS NO.:25316-40-9
Doxorubicin Hcl EINECS:246-818-3
Doxorubicin Hcl Molecular Formula:C27H29NO11.HCl
Doxorubicin Hcl Molecular Weight:579.99
Doxorubicin Hcl Appearance:Orange powder

 

Doxorubicin,also known as hydroxydaunorubicin and hydroxydaunomycin, is a drug used in cancer chemotherapy and derived by chemical semisynthesis from a bacterial species.It is an anthracycline antitumor antibiotic (note: in this context, this does not mean it is used to treat bacterial infections) closely related to the natural product daunomycin and like all anthracyclines, it works by intercalating DNA, with the most serious adverse effect being life-threatening heart damage.

 

It is commonly used in the treatment of a wide range of cancers, including hematological malignancies (blood cancers, like leukaemia and lymphoma), many types of carcinoma (solid tumours) and soft tissue sarcomas.It is often used in combination chemotherapy as a component of various chemotherapy regimens.

 

Doxorubicin Hydrochloride Basic Info.

Synonyms:Doxorubici hydrochloride, Adriacin, Doxorubici, Adriamycin;
Assay:99%
CAS No.:25316-40-9
MF:C27H30CLNO11
MW:579.98
Appearance:Orange-red or red crystalline powder;
Storage:Keep in a dry, cool and ventilated place
Category:Raw anabolic material for the treatment of cancer

Doxorubici Hydrochloride Description:
It is a drug used in cancer chemotherapy. It is an anthracycline antibiotic, closely related to the natural product daunomycin, and like all anthracyclines, it works by intercalating DNA, with the most serious adverse effect being life-threatening heart damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.

Doxorubici Hydrochloride Applications:
1 Hodgkins disease and lymphosarcoma, reticulum cell sarcoma.
2 undifferentiated small cell and non-small cell lung cancer, breast cancer.
3 acute lymphoblastic and myeloid leukemia.
4 osteosarcoma and soft tissue sarcoma.
5 ovarian cancer, testicular cancer, bladder cancer, . Wilms cancer, prostate cancer, thyroid cancer, neuroblastoma cancer, esophageal cancer, stomach cancer, liver cancer, cervical cancer and head and neck cancer. Multiple myeloma, pancreatic cancer, endometrial cancer and brain tumors can also be applied.

 

Doxorubicin hydrochloride COA:

Product Name Doxorubicin hydrochloride(C27H30ClNO11) CAS:25316-40-9
Items Tested Specification Result
Purity 98.0~102.0% 99.02%
Description Orange-red or red crystalline powder; No visible
evidence of contamination by foreign matter.
Confirm
Identification A IR spectrum corresponds to the IR spectrum of the reference standard Confirm
Identification B The retention time of the doxorubicin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. Confirm
Solubility Soluble in water and methanol; slightly soluble in ethanol; practically insoluble in acetone. Conforms
Residual Solvents    
Acetone ≤ 0.5% 0.31%
Acetone +Ethanol ≤ 2.5% 0.60%
methanol ≤ 0.3% Not detected
Dichloromethane ≤ 0.06% Not detected
pH 4.0 to 5.5 5.1
Water Content ≤ 4.0% 0.8%
Related Substances    
Impurity A (Doxorubicinone) ≤ 0.5% 0.1%
Any Other unknown Impurity ≤ 0.1% 0.07%
Total unknown Impurities ≤ 0.3% 0.2%
Total Impurities ≤ 1.0% 0.9%
Conclusion It complies to reference standard
   
     

Uses: This product is suitable for breast cancer, lung cancer, soft tissue tumors, osteosarcoma, bladder cancer, testicular cancer, thyroid cancer, neuroblastoma cancer, Wilms cancer, malignant lymphoma and acute leukemia, can also be used for liver cancer, stomach cancer, ovarian cancer, cervical cancer, head and neck cancer, multiple myeloma, pancreatic cancer, esophageal and endometrial tumors.

Description;

Doxorubicin Hydrochloride is the hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects.

Doxorubicin hydrochloride is also being studied in the treatment of other types of cancer.
Doxorubicin hydrochloride is also available in a different form called doxorubicin hydrochloride liposome.

Specifications:

English name: DOXORUBICIN HCL
Alias: DOXORUBICIN HCL
CAS 25316-40-9
Molecular formula C27H30ClNO11
Molecular weight 579.98
Content 99%
Appearance orange-red loose-like lumps or powder
Price negotiate
MOQ 20g
payment T/T , West Union , Money Gram
Packing: According to customer requirements for packaging
Shipping way DHL, TNT, FEDEX, HKEMS, UPS
Shipping fee Within 500g is $45
Delivery time Within 24 hours after you pay and should arrive your hands within 7 days
After-sales service Give you the tracking number ASAP after your products send out

Also will give you the way to help you convert the powder into injection


Our advantage:

Package Do not need to worry about the customs problem,we will use discreet package,very safe.
Fast Delivery about 4-7days by TNT, FedEx, EMS, DHL(Door-to-Door).
Quality GMP lab to guarantee the quality with good price
Sample Sample available at any time
Resend If your parcel is lost or detained, please inform me immediately, We will re-send your parcel, this is our policy
Payment Terms Western Union/ Money Gram/ Bank Transfer/ Bitcoin/ Paypal for your option.
 

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Pharmaceutical Raw Materials Anti-Cancer Doxorubicin Hydrochloride Powder CAS: Images

 

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