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Pharmaceutical Raw Materials Telmisartan Raw For Antihypertensive Treatment

Place of Origin:
HUBEI,CHINA
Brand Name:
HKYC
Certification:
ISO 9000, SGS
Model Number:

Pharmaceutical Raw Materials

Min.Order Quantity:
10grams
Price:
negotiable(best offer will be provided)
Packaging Details:
designed disguised packing ways, 100% pass custom guarantee)
Delivery Time:
within 24hours after payment confirm
Payment Terms:
MoneyGram, Western Union, T/T, Bitcoin
Supply Ability:
1000Kg per Month
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Product Description

Pharmaceutical Raw Materials Telmisartan raw for Antihypertensive Treatment

 

1.Basic Info:

Product Name Telmisartan
CAS 144701-48-4
MF C33H30N4O2
MW 514.63
Purity 99%
Appearance White or off-white crystalline powder
Usage cardiotonic. an angiotensin II receptor antagonist. anti-cancer agent
Categorie Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;INTERMEDIATESOF;Antihypertensive;Imidazoles;(intermediates of telmisartan);Telmisartan;Hypertension;Intermediates & Fine Chemicals;Pharmaceuticals;APIs;Other Products;Hypertension.;CARADRIN
Synonyms TU-199;TELMISARTAN;PRITOR;MICARDIS;BIBR 277;
4[(1,4-DIMETHYL-2-PROPYL[2,6-BI-1H-BENZIMIDAZOL]-1-YL)METHYL][1,1-BIPHENYL]-2-CARBOXYLIC ACID;
4-[(1,4-DIMETHYL-2-PROPYL[2,6-BI-H-BENZIMIDAZOL]-1-YL)METHYL][1,1-BIPHENYL]-2-CARBOXYLIC ACID;
3-methoxy-8-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methyl sulfinyl]-2,7,9-triazabicyclo[4.3.0]nona-2,4,8,10-tetraene


COA:

Items Specification Results
Appearance White or slightly yellowish crystalline powder White crystalline powder
Solubility Should meet the requirement Conforms
IR Identification Should correspond to the RS Infrared Absorption Correspond to the reference substance
Appearance of solution Should meet the requirement Conforms
Loss on drying ≤0.5% 0.20%
Sulphated ash ≤0.1% Conforms
Melting point 261 ºC -263 ºC 261.1 ºC -262.2 ºC
Particle size 90% Less than 200um Conforms
Assay 99.0%~101.0% 99.9%
Conclusion It conforms to European Pharmacopoeia 7.0


 





2.Description

Telmisartan (Micardis) is an oral prescription medication most commonly used to treat hypertension, including mild hypertension where blood pressure is only moderately elevated or borderline. If choosing to self-medicate for mild hypertension or borderline high blood pressure, telmisartan is an excellent or even best choice.

As elevated blood pressure is often an undesired side effect of anabolic steroid cycles and can even limit use of androgens, this use of telmisartan is already enough to make the drug of value to many.
However, telmisartan also has an entirely different category of use, due to having quite a number of other interesting properties which can be valuable in some instances.

Benefits can include improvement to fat loss, endurance, insulin sensitivity, reduction of risk of atherosclerosis, stroke, and of heart attack, and possible benefit to brain health. In some cases mood or energy can be improved as well.




3.Application :

1. Telmisartan is an angiotensin II receptor antagonist. Telmisartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

2. Telmisartan is used to treat high blood pressure (hypertension). It is sometimes given together with other blood pressure medications.

3. Telmisartan is also used to reduce the risk of stroke, heart attack, or death from heart problems in people who are at least 55 years old with risk factors for serious heart disorders.




4.When to use telmisartan

If blood pressure needs to be moderated, Id certainly consider using telmisartan. If there is no such need, factors that could suggest its use include interest in reducing visceral fat, of improving impaired insulin sensitivity, of reducing risk of atherosclerosis, or depending on personal interest, of possibly improving brain health and function.

Reasons not to use telmisartan could include unwillingness to accept the risk of possible side effects, or unwillingness to shift the balance of fat loss towards visceral fat loss versus subcutaneous fat loss. In general, if dieting and training achieve only the same bodyfat percentage despite the positive effects of telmisartan, appearance could be smoother due to the same amount of bodyfat being present but with less of it stored as unhealthful visceral fat.
On the other hand, if taking advantage of improved loss of visceral fat with telmisartan to achieve a lower bodyfat percentage, then theres no smoothness penalty. However, when aiming for contest condition theres a certain amount of fat that the body must retain: theoretically, reducing visceral fat in this case might force retention of a greater amount of subcutaneous fat. So I wouldn advise telmisartan use in the last few weeks before a bodybuilding contest.




5.How to use telmisartan

To reduce risk of atherosclerosis, cardiovascular disease, or stroke where risk is only moderate in the first place, I suggest a dose from 20 to 40 mg taken orally once per day. Dosing would be the same where the interest is slowing loss of brain function with age, or potentially improving brain function.

For possible improvement in fat loss, particularly of visceral fat, or improvement of endurance I suggest dosing of 80-160 mg/day. Starting dose, however, generally should be only 40 mg/day until tolerance is assessed.

While its not required and telmisartan users in general do not do so, when using this drug I suggest supplementing with oleuropein 200-400 mg/day and Vitamin D 5000 IU/day. These are to reduce or perhaps eliminate two activities of telmisartan that I would not consider desirable for physique or performance enhancement, though they add to its medical use.

Telmisartan should not be used in combination with a diuretic, and I would avoid allowing severe dehydration while using this drug.

Blood pressure should be monitored while using telmisartan. Typically, any decrease of blood pressure is simply to healthful levels or more-nearly healthful levels, and those who do not have high blood pressure see no decrease with telmisartan. Still, there can be exceptions, so this should be watched.

Lastly, I would cycle telmisartan use rather than use it continuously. Theres no proof of what cycling method might be optimal, but for example Id suggest being "off" about as many weeks per year as "on" as a minimum. This is not because of proven problem, but simply because I expect the benefits can be fully or nearly fully realized with this amount of use, and where any of the changes to gene expression or receptor blocking might be adverse in the individual case rather than beneficial, this will then be no more than half the time.

 
 

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