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HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

Home > Products > Pharmaceutical Raw Materials > Anti Allergic Pharmaceutical Raw Materials Ketotifen Fumarate For Antiasthmatic
 

Anti Allergic Pharmaceutical Raw Materials Ketotifen Fumarate For Antiasthmatic

  • Anti Allergic Pharmaceutical Raw Materials Ketotifen Fumarate For Antiasthmatic
Place of Origin:
HUBEI,CHINA
Brand Name:
HKYC
Certification:
ISO 9000, SGS
Model Number:

Pharmaceutical Raw Materials

Min.Order Quantity:
10grams
Price:
negotiable(best offer will be provided)
Packaging Details:
designed disguised packing ways, 100% pass custom guarantee)
Delivery Time:
within 24hours after payment confirm
Payment Terms:
MoneyGram, Western Union, T/T, Bitcoin
Supply Ability:
1000Kg per Month
Contact Now
 

Product Description

Anti Allergic Pharmaceutical Raw Materials Ketotifen Fumarate For Antiasthmatic

 

Ketotifen fumarate Basic Info

 

Product Name Ketotifen fumarate
Alias Allerkif , Anatifen, Ketotifen Hydrogen FuMarate, EP
CAS 34580-14-8
MF C23H23NO5S
MW 425.5
EINECS 252-100-0
Purity 99.50%
Grade Pharmaceutical Grade
Appearance White Crystal Powder
Brand Nmae HKYC
Standard EP 7
Stock Mass Stock
Packing Methods designed disguised packing ways, 100% pass custom guarantee
Delivery time within 18 hours after payment confirmed
Payment T/T, Western Union,Money Gram , Bitcoin
Usage Ketotifen fumarate is a kind of strong anti-allergic drugs containing simultaneously of both tricyclic structure as well as piperidine structure.

 

Ketotifen fumarate Descrption

 

Ketotifen fumarate is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt of fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis, or the itchy red eyes caused by allergies. In its oral form, it is used to prevent asthma attacks. Side effects include drowsiness, weight gain, dry mouth, irritability, and increased nosebleeds.

 

Ketotifen fumarate Usage And Synthesis

Ketotifen fumarate is a kind of strong anti-allergic drugs containing simultaneously of both tricyclic structure as well as piperidine structure.

 

Ketotifen fumarate is characterized by both a strong antagonism effect on histamine H1 receptor and inhibitory effect of the release of the mediator of allergic reaction.

 

Ketotifen fumarate can inhibit the release various kinds of mediators of mast cells, basophils and macrophages, including the release of slow reacting substances and other active substances.

 

Ketotifen fumarate also has antagonism effect on the calcium ion; can inhibit the activity of phosphodiesterase; increase the intracellular cAMP level inside mast cells.

 

Moreover, Ketotifen fumarate can also inhibiting the chemotaxis and inflammation of neutrophil with an effect 10 times as strong as that of chlorpheniramine, and it also has a long duration time which is better compared with sodium cromolyn.

 

Ketotifen fumarate has therapeutic effect on both I and III type of allergic reaction. Its peak blood concentrations can sustain for 2 to 3 hours with a half-life of 22 hours during which 60% goes through urinary excretion, 40% goes through the fecal excretion. Children usually have a faster excretion rate of it than adults. Long-term treatment will not cause resistance. No rebound phenomenon will occur with interruption of treatment.

 

Ketotifen fumarate Specification

 

Test Specifications Result
Appearance White to brownish-yellow,fine,crystalline powder White powder
Solubility Sparingly soluble in water, slightly soluble in Methanol,very slightly soluble in acetonifrile Complies
Identification TLC/IR spectrum Complies
Clarty and colour Clear and not more than Y4,BY4,B4 < BY4
Loss on drying Not more than 0.5% 0.24%
Sulphated ash Not more than 0.1% 0.04%
Impurity A Not more than 0.2% 0.07%
Impurity G Not more than 0.2% Not detected
Single unkown Impurity Not more than 0.1% Complies
Total Impurity Not more than 0.5% 0.16%
Acetone ≤5000ppm ≤5000ppm
Methanol ≤500ppm <1ppm
Assay Between 98.5% and 101.0% 99.50%
Conculsion The results can conform to EP7 Standard

 

 

You may want to know First :

 

1. Available: steroid powder, semi-finished oil, sarms, peptides pain killers etc. And all kinds of machines for  steroids processing.

 

2. Parcel : Designed Discreet packing according to different countries and quantity.

 

3. Pass Custom Rate: more than 99%.

 


5. Delivery Methods: EMS, DHL, FedEx, UPS, TNT, Aramex, China/Hongkong/ Singapore/Sweden/Holland Post Mail. All with tracking code. Usual delivery time is 4-7 workdays.

6.Delivery Time: US :3-5 days, UK: 4-7 days, Canada: 3-7 days, Europe: 6-10 days

 

Packaging & Service:


1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 25 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking code are provided within 24 hours as soon as receiving the payment. Updated tracking code will be provided every other day just for you can hold a palm of your package.
5. Perfect after-sale service: Any questions or problems happened after receiving the product.

 

 

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