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HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

Home > Products > Pharmaceutical Raw Materials > Inhibitor Pharmaceutical Raw Material CAS 284461-73-0 Sorafenib For Anti-Tumor
 

Inhibitor Pharmaceutical Raw Material CAS 284461-73-0 Sorafenib For Anti-Tumor

  • Inhibitor Pharmaceutical Raw Material CAS 284461-73-0 Sorafenib For Anti-Tumor
Place of Origin:
HUBEI,CHINA
Brand Name:
HKYC
Certification:
ISO 9000, SGS
Model Number:

Diclofenac Sodium

Min.Order Quantity:
10grams
Price:
negotiable(best offer will be provided)
Packaging Details:
foil bag or as your mind
Delivery Time:
within 24hours after payment confirm
Payment Terms:
MoneyGram, Western Union, T/T, Bitcoin
Supply Ability:
1000Kg per Month
Contact Now
 

Product Description

Inhibitor Pharmaceutical Raw Material CAS 284461-73-0 Sorafenib For Anti-Tumor

 

 

Sorafenib basic info

 

Product Name Sorafenib
Alias Sorafenib Free Base, Forafenib
CAS 284461-73-0
MF C21H16ClF3N4O3
MW 464.83
Purity 99.50%
Grade Pharmaceutical Grade
Appearance white Crystalline Powder
Brand Nmae HKYC
Standard USP
Stock Mass Stock
Shelf Life 2years
Packing Methods foil bag or as your mind
Delivery time within 18 hours after payment confirmed
Payment T/T, Western Union,Money Gram , Bitcoin
Usage Sorafenib is a Kinase Inhibitor.
Sorafenib is an antineoplastic agent.

 

Sorafenib Descrption

 

Sorafenib is a new multi-targeted oral drug for the treatment of tumors. Its primary development goal is to treat gastrointestinal stromal tumors and metastatic kidney cells that are not responsive or unbearable to standard therapies.

 

Sorafenib can selectively target certain proteins of the receptor, which is considered plays a role in molecular switching in the tumor growth process. Its indications have been in the approval by the FDA United States.

 

Sorafenib Application

 

1. Sorafenib tosylate (284461-73-0) is commonly used as a potent RAF kinase inhibitor.

2. Sorafenib tosylate (284461-73-0) is also used as antineoplastic drug.

3. Sorafenib is used to treat liver tumor cells that can not be surgically or distantly metastasized

4. Sorafenib is used to treat neovascular tumors that can not be operated

5. Sorafenib is used to treat radioactive iodine therapy is no longer effective local recurrence or metastasis, progressive differentiation of thyroid patients

 

Sorafenib VS placebo

 

The progression-free survival of the Sorafenib group was longer than that of the placebo group (5.8 vs 2.8 months at a risk ratio of 0.51), and Sorafenib significantly improved patient quality of life compared with placebo.

 

Sorafenib treatment is well tolerated, with major adverse reactions being controlled diarrhea, rash, fatigue, hand, foot syndrome, hypertension, hair loss, nausea / vomiting and loss of appetite.

 

Sorafenib Recommend Dosage

 

Recommended Dosage: Sorafenib is recommended for 0.4 g (2x0.2g) twice daily for fasting or with low fat and lipid diet.

The clear half-life of sorafenib is about 25-48 hours. Compared with single dose administration, repeated administration of 7 days to achieve 2.5-7 times the accumulation.

 

After 7 days of administration, the plasma concentration of sorafenib reached steady state, and the average plasma concentration was less than 2.

 

Sorafenib was given about 3 hours after oral administration to the highest plasma concentration. Moderate fat diet is similar to bioavailability under fasting conditions. In the high quality diet, the bioavailability of sorafenib was reduced by 29% compared with the fasting state.

 

When the oral formulation exceeds 0.4 g twice daily, the increase in Cmax and AUC is not linear.

In vitro, sarafenib and human plasma protein binding rate of 99.5%.

 

Sorafenib Specification

 

Items Specifications Results
Appearance White to light yellow crystalline powder complies
Solubility

In methanol, ethanol, ethyl acetate very slightly soluble

in water almost insoluble

complies
Any single impurity ≤0.2% 0.06%
Loss on drying ≤1.0% 0.06%
Residue on ignition ≤0.1% 0.03%
Assay ≥99.5% 99.87%
Conculsion The results conform to the Specification
 

 

 

About US

 

Welcome to HKYC. Our company specialize in pharmaceutical raw materials, like anti-depression drug raw material , anti acne drug raw material, antibiotic raw material, Nootropics Drug raw material, Nervous System Drug raw material, Local Anaesthetic Agents, steroid hormone, sarms, peptides and pain killers etc.

 

We always willing to make a better deal for you. For regular customers we are giving great offers.

Once one become our customer, he will definitely return for another order.

 

Our mission is to provide our customer with an excellent personal service which develops long-term relationship, meeting their specific needs within budget and time frame. Ensure regulatory compliance are maximize on clients core competencies and product quality through optimized validated and controlled processes.

 

We have customer desired packing methods chosen and recommended by most of our customers.

We do pack as the customer desires the package to be packed....

 

All products are produced under GMP conditions according to Standard Operation Procedure(SOP),

not from little underground labs or black markets, so the quality is guaranteed.

 

Prices depends on your order but we always encourage new clients to place sample / small orders and check our service,

products and our communication and then gradually do your regular business with us. Of course bulk orders will enjoy discounts.

 

All products are bulk in stock, usually ship within 24-48 hours of your order being received and processed. Fast Express Delivery ,Available with UPS,FedEx,EMS,DHL,TNT and so on,

secure shipping and fast T/A. US :3-5 days, UK: 4-7 days, Canada: 3-7 days, Europe: 6-10 days

 

If you need quality products and timely delivery then you do not need to go anywhere else,

just contact us and we serve you a lot better then anyone else.

 

 

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