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HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

Home > Products > Pharmaceutical Raw Materials > Active Pharmaceutical Ingredients CAS 220127-57-1 Imatinib Mesylate White powder
 

Active Pharmaceutical Ingredients CAS 220127-57-1 Imatinib Mesylate White powder

  • Active Pharmaceutical Ingredients CAS 220127-57-1 Imatinib Mesylate White powder
Place of Origin:
HUBEI,CHINA
Brand Name:
HKYC
Certification:
ISO 9000, SGS
Model Number:

Pharmaceutical Raw Materials

Min.Order Quantity:
10grams
Price:
negotiable(best offer will be provided)
Packaging Details:
foil bag or as your mind
Delivery Time:
within 24hours after payment confirm
Payment Terms:
MoneyGram, Western Union, T/T, Bitcoin
Supply Ability:
1000Kg per Month
Contact Now
 

Product Description

Active Pharmaceutical Ingredients CAS 220127-57-1 Imatinib Mesylate White powder

 

 

Imatinib Mesylate Basic information

 

Product Name Imatinib Mesylate
Alias Imatinib Methanesulfonate, STI-571, CGP-57148B, Glivec
CAS 220127-57-1
MF C30H35N7O4S
MW 589.71
Purity 99.50%
Grade Pharmaceutical Grade
Appearance white Crystalline Powder
Brand Nmae HKYC
Standard USP
Stock Mass Stock
Shelf Life 2years
Packing Methods foil bag or as your mind
Delivery time within 18 hours after payment confirmed
Payment T/T, Western Union,Money Gram , Bitcoin
Usage Imatinib Mesylate is mainy used for anti tumor
Imatinib Mesylate is a tyrosine kinase inhibitor

 

Imatinib Mesylate Product Description

 

Imatinib mesylate is a tyrosine kinase inhibitor IC50 value of 100 nM, 100 nM, 600 nM for v-Abl, c-kit, PDGFR, respectively.

 

Imatinib Mesylate is a specific tyrosine kinase (abl, c-kit, and PDGFR) inhibitor and is reported to sensitize cells to radio- or chemo-therapy. When tested with Y-79 and WERI-RB-1 Rb cell lines, imatinib mesylate treatment decreased the cell proliferation and invasion with the concentration of 10 μM . In osteoblast cells, administration of imatinib mesylate decreased osteoclast development via stimulating differentiation, inhibiting proliferation and survival .

 

In dog model with mast cell tumor, administration of imatinib mesylate at a dose of 10 mg/kg daily for 1-9 weeks reduced tumor growth via inhibiting tyrosine kinase .

 

Imatinib Mesylate Applications

 

Cells were stimulated with allogeneic mature DCs or PHA in the presence of imatinib mesylate. The drug inhibited T-cell proliferation as a function of concentration. The effects were significant at 0.5 μM imatinib mesylate for the cells stimulated by DCs and at 1.0 μM imatinib mesylate for the cells stimulated with PHA. The IC50 values for imatinib mesylate-inhibited T-cell proliferation stimulated by DCs and PHA were 3.9 μM and 2.9 μM, respectively..

 

A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)

 

Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib also known as Gleevec, Glivec, CGP-57148B, STI-571 & Imatinib

 

Imatinib Mesylate (STI571) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.

 

echinocandin antifungal, active against infections with Aspergillus and Candida, inhibits cell wall synthesis

 

 Dosage

 

Starting dose: in patients with chronic myelogenous leukemia radically increasing stage and accelerating stage, imatinib mesylate in the recommended dose of 600 mg/day; Chronic-phase of interferon treatment failure, and cannot be removed surgically or metastatic malignant gastrointestinal stromal tumors (GIST) patients, and the recommended dose of 400 mg/day, both for once-daily oral, appropriate medication when eating, and drinking a glass of water, as long as effective, should be continued.


 

About US

 

Welcome to HKYC. Our company specialize in pharmaceutical raw materials, like anti-depression drug raw material , anti acne drug raw material, antibiotic raw material, Nootropics Drug raw material, Nervous System Drug raw material, Local Anaesthetic Agents, steroid hormone, sarms, peptides and pain killers etc.

 

We always willing to make a better deal for you. For regular customers we are giving great offers.

Once one become our customer, he will definitely return for another order.

 

Our mission is to provide our customer with an excellent personal service which develops long-term relationship, meeting their specific needs within budget and time frame. Ensure regulatory compliance are maximize on clients core competencies and product quality through optimized validated and controlled processes.

 

We have customer desired packing methods chosen and recommended by most of our customers.

We do pack as the customer desires the package to be packed....

 

All products are produced under GMP conditions according to Standard Operation Procedure(SOP),

not from little underground labs or black markets, so the quality is guaranteed.

 

Prices depends on your order but we always encourage new clients to place sample / small orders and check our service,

products and our communication and then gradually do your regular business with us. Of course bulk orders will enjoy discounts.

 

All products are bulk in stock, usually ship within 24-48 hours of your order being received and processed. Fast Express Delivery ,Available with UPS,FedEx,EMS,DHL,TNT and so on,

secure shipping and fast T/A. US :3-5 days, UK: 4-7 days, Canada: 3-7 days, Europe: 6-10 days

 

If you need quality products and timely delivery then you do not need to go anywhere else,

just contact us and we serve you a lot better then anyone else.

 

 

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