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  • Phenacetin /4-ACETOPHENETIDIDE/ACETOPHENETIDIN CAS 62-44-2 Pain Relieving
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Product Description


Quick Detailed:

Phenacetin MF: C10H13NO2 Phenacetin MW: 179.22

Phenacetin EINECS: 200-533-0 Phenacetin mp: 133-136 °C(lit.)
Phenacetin bp 1:32 °C / 4mmHg Phenacetin storage temp: 2-8°C
Phenacetin Water Solubility : 0.076 g/100 mL Phenacetin Sensitive: Hygroscopic
Phenacetin Merck :14,7204 Phenacetin BRN :1869238
Phenacetin Stability: Stable. Incompatible with strong oxidizing agents, strong acids.

Product Description:

Hot Anesthetics Raw Material Phenacetin/Phenacet with Safetest Delivery Acetophenetidin
Phenacetin Local Anesthetics Pharmaceutical Material
Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C." or aspirin-phe-nacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincents APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phe-nacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)). It was also banned in India.As a result some branded, previously phe-nacetin-based preparations continued to be sold, but with the phe-nacetin replaced by safer alternatives. A popular brand of phe-nacetin was Roches Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phe-nacetin.

Usage and Effects:

Phenacetin Usage Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.

Paracetamol is a metabolite of phe-nacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phe-nacetins carcinogenicity.
Phenacetin is now being used as a cutting agent to adulterate in the UK and Canada, owing to the similar physical features of the two drugs.
Glycosylation inhibitor

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