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White Powder Pharmaceutical Raw Materials Poloxamer 407 9003-11-6 ISO 9001

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Product Description

White Powder Pharmaceutical Raw Materials Poloxamer 407 9003-11-6

Product Name Poloxamer 407

Poloxamer 407 Alias Plurnic,Poloxalkol,Monolan,Supronic,Synperonic

Poloxamer 407 CAS 9003-11-6

Poloxamer 407 MF HO·(C2H4O)m·(C3H6O)n·H

Poloxamer 407 MW 102.13

Poloxamer 407 Assay 71.5%

Poloxamer 407 Grade Pharmaceutical Grade

Poloxamer 407 Appearance White Powder

Poloxamer 407 Description

This product is mainly used as thickening agent and gel forming agent, in the cream and emulsion used as emulsifier and increases the degree of improver, used for industrial, cosmetic field;As in the pharmaceutical industry, it can be used as a certain yao content of active ingredients of the solvent, eye drops.As the local and the dosage of suspension stabilizer through the mouth;In the daily chemical product used as viscosity improver;In addition this product can also be used in toothpaste, mouthwash and mouthwash.

Poloxamer is a kind of non-ionic surface active agent, is a kind of new pharmaceutical excipients. Features: 1, increase the solubility of;2, as the emulsifier and stabilizer;3, can be used as a slow release materials;4, as cream preparation, suppository matrix;5, in ocular drug delivery system has a good effect.

Poloxamer 407 is a synthetic block copolymer of ethylene oxide and propylene oxide. It is available in several types. This kind of surfactant were firstly developed by America.They have almost no toxicity, little irritation on the skin and the mucosa. They are widely used as emulsifier, solubilizing agent, hydrophilic substrate of ointments and suppositories,artificial blood, artificial tear and artifical skin etc.


(1) to strengthen stamina, vigour and physical strength;

(2) to improve the reactive sensitivity;

(3) to improve the stress strength;

(4) to promote function of sex hormone, ease the pain of muscle;

(5) to improve the function of cardiac muscle,

(6) to reduce cholesterol, blood fat and systolic pressure;

(7) to improve the organism metabolism.

poloxamer 407 quick details:

Item Standard Results
Unsaturation,% ≤0.034 0.027
Oxyethylene(%) 71.5~74.9 73.86
Heavey metal ≤20ppm Pass
Free ethylene oxide ≤1ppm 0.7
Propylene oxide ≤5ppm 0
1,4-dioxane ≤5ppm 0
PH 5.0~7.5 6.81
Water ≤1.00% 0.15%
Total ash ≤0.4% 0.12%
Hydroxyl value 4.0-14.0 9.36
clarity of solution Accord to JP Pass
acid Accord to JP Pass
alkali Accord to JP Pass
Identification Accord to JP Pass
Arsenic ≤0.0002% Pass

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