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HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

Home > Products > Pharmaceutical Raw Materials > Cefpirome Sulfate Cephaquine Antibiotics Raw Materials For Pharmaceutical
 

Cefpirome Sulfate Cephaquine Antibiotics Raw Materials For Pharmaceutical

  • Cefpirome Sulfate Cephaquine Antibiotics Raw Materials For Pharmaceutical
Place of Origin:
china
Brand Name:
hkyc
Certification:
iso
Model Number:

Antibiotics

Min.Order Quantity:
100gram
Price:
USD
Packaging Details:
1KG/foil bag, 25kg/drum
Delivery Time:
5-8WORKING DAYS
Payment Terms:
T/T, Western Union, MoneyGram
Supply Ability:
500KG PER WEEK
Contact Now
 

Product Description

Cefpirome Sulfate Cephaquine 98753-19-6 Antibiotics Pharmaceutical Raw Materials

Cephaquine

Chinese Name: Cephaloquine

English name: Cefpirome sulfate

CAS Number: 98753-19-6

Molecular Formula: C22H24N6O9S3

Quality Standard: JP15

Molecular weight: 612.66

Packaging 5KG/listening

Characters: Cefquinim is a fourth-generation cephalosporin co-developed by Hoechst GmbH of Germany and Roussel of France. It is a new-generation cephalosporin that has been used in foreign countries in recent years, and it is the first, second and third generation cephalosporins. Compared to bacteriocin, the fourth-generation cephalosporins have a broader antibacterial spectrum, are more stable to β-lactamase, have high blood concentration, and can penetrate the blood-brain barrier.

Uses: Used in hospitals and communities for severe lower respiratory tract infections; infections in patients with leukopenia; severe infections in intensive care patients; sepsis/bacteremia; skin and soft tissue infections; complex upper and lower urinary tract infections; meningitis, etc. treatment.

Mechanism of action:

This product has a strong antibacterial effect, broad spectrum of antibacterial, Gram-positive bacteria (such as Staphylococcus, Enterococcus faecalis), Gram-negative bacteria (such as Branceria, Pseudomonas) and anaerobic bacteria Has a wide spectrum of antibacterial and strong bactericidal effect. It has high stability against β-lactamase and can metastasize to sputum, bile, intraperitoneal, wound exudate, female sexual organs, prostate and cerebrospinal fluid. It has been clinically proven to have a good effect on superficial secondary infections such as sepsis, trauma and surgical trauma. Cefpirome has good bactericidal activity against bacterial meningitis pathogens, and has good penetrability on the blood-brain barrier, so this product has achieved good results in the treatment of meningitis infection. Although the half-life of cefpirome is relatively short (about 2 hours), the concentration of the drug in body fluids is high, and the amount of cefquinome can be appropriately reduced, so that satisfactory antibacterial effects can be achieved and treatment costs can be reduced.

 

Cefoperazone Sodium


Contents of Testing

Requirements

Results of Analysis

Description

White crystalline Powder

Meets the requirements

Identification

Meets the requirements

Meets the requirements

pH

4.5~6.5

5.0

Water

≤5.0%

3.2%

Crystallinity

Meets the requirements

Meets the requirements

Bacterial endotoxin

≤0.20 EC/mg

Meets the requirements

Sterility

Meets the requirements

Meets the requirements

Particulate matter

Meets the requirements

≥10um

NMT 6000/G

≥25um

NMT 600/G

Assay

870~1015ug/mg

937 ug/mg



Cefoperazone Sodium & Sulbactam sodium 1:1, 2:1

Product name Cefoperazone Sodium & Sulbactam Sodium 1:1
Items Specification Results
Appearance white or almost white powder complies
Identification 1) HPLC: The retention time of the two major peaks in the chromatogram of the Assay preparation corresponds to those in the chromatogram of the standard preparation, as obtained in the Assay complies
2) Sodium reaction complies
Ph 3.5-6.5 5.2
Clarity and color of solution clarity ≤1# <0.5#
color ≤Y4# or YG4# <YG2#
Related substances Cefoperazone Impurity A ≤1.5% 0.3%
Any other impurity ≤1.5% 1.2%
Total impurities ≤5% 2.6%
Water ≤4.0% 2.1%
Bacterial endotoxins <0.05EU/mg <0.05EU/mg
Sterility meets the requirement complies
Visible particles ≤5/4.0g complies
Particulate matter ≥10μm particles: ≤6000/4.0g 335
≥25μm particles: ≤600/4.0g 10
Assay(anhydrous basis) Cefoperazone (C25H27N9O8S2) ≥435μg/mg 449μg/mg
Sulbactam (C8H11NO5S) ≥445μg/mg 464μg/mg
Residual solvents meets the requirements complies


Cefoperazone Acid

ITEMS SPECIFICATION RESULTS
Appearance White to pale yellow Crystalline Powder Passed
Identification IR Spectrum
HPLC RT
Sodium
Passed
Passed
Passed
Clarity Clear Passed
Color of Solution NMT 0.2(430mm,10% solution) Passed
Specific optical rotation +56°~+64° +61°
PH 4.5~6.5 5.5
Loss on drying ≤3.0% 2.7%
Chromatographic purity
Individual impurity
Total impurity

≤1.0%
≤3.0%

≤0.6%
≤2.0%
Sterility Sterile Passed
Bacterial Endotoxins NMT 0.20 USP EU/mg Passed
Particulate matter ≥10um NMT 6000
≥25 um NMT 600
Passed
Passed
Assay(HPLC) 916-964μg/mg 940μg/mg



Cefpirome Sulfate
Cefpirome sulfate (CAS:98753-19-6 ) is a fourth-generation cephalosporin. Trade names include Cefrom, Keiten, Broact, Cefir. Cefpirome is considered highly active against Gram-negative bacteria, including Pseudomonas aeruginosa, and Gram-positive bacteria.

Product Name Cefpirome sulfate
Quality Standard JP15 / USP30
Specification pure powder / containing carbonate sodium mixed powder
Appearance white crystalline powder
PH 1.0-2.6
Assay 820ug / mg
Moisture ≤0.5%
Residue on ignition ≤0.5%
Uses pharmaceutical raw materials, cephalosporin antibiotic fungi
 
 

Cefpirome Sulfate Cephaquine Antibiotics Raw Materials For Pharmaceutical Images

 

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