White Powder Furosemide Treatment of hypertension And Edema CAS 54-31-9
Furosemide, sold under the brand name Lasix among others,is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.It may also be used for the treatment of high blood pressure. The amount of medication required depends on the person in question. It can be taken intravenously or by mouth. When taken by mouth it typically begins working within an hour while intravenously it typically begins working within five minutes.
Common side effects include low blood pressure with standing, ringing in the ears, and sensitivity to the sun. Potentially serious side effects include electrolyte abnormalities, low blood pressure, and hearing loss. Blood tests are recommended regularly for those on treatment. Furosemide is a type of loop diuretic that works by decreasing the reabsorption of sodium by the kidneys.
Furosemide was discovered in 1962.It is on the World Health Organizations List of Essential Medicines, the most effective and safe medicines needed in a health system.Furosemide is on the World Anti-Doping Agencys banned drug list due to concerns that it may mask other drugs. It has also been used to prevent and treat race horses for exercise-induced pulmonary hemorrhage.
Product name: Furosemide
Synonyms: LABOTEST-BB LT00244801;FUROSEMID;FUROSEMIDE;FRUSEMIDE;2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid;4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID;5-(AMINOSULPHONYL)-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID;5-[AMINOSULFONYL]-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID
Furosemide (Lasix) for injection
Furosemide is primarily used for the treatment of hypertension and edema. It is the first-line agent in most people with edema caused by congestive heart failure.It is also used for hepatic cirrhosis, renal impairment, nephrotic syndrome, in adjunct therapy for cerebral or pulmonary edema where rapid diuresis is required (IV injection), and in the management of severe hypercalcemia in combination with adequate rehydration.
In chronic kidney diseases with hypoalbuminemia, it is used along with albumin to increase diuresis. It is also used along with albumin in nephrotic syndrome to reduce edema.
Excreted by tubular secretion, therefore in severe renal impairment (GFR 5-10 ml/min) lower doses are required due to accumulation in the body. It also can cause further renal damage and should be administered with caution.
Furosemide acts within 1 hour of oral administration (after IV peak effect within 30 minutes); diuresis is complete within 6 hours (for oral administration) and 2 hours (for IV administration).
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