Nootropic Supplements Sunifiram / DM235 For Memory Enhancement , CAS 314728-85-3
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Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).
This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation.
Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.
Synonyms:Piperazine, 1-benzoyl-4-(1-oxopropyl)-/SunifiraM/1-(4-Benzoyl-1-piperazinyl)-1-propanone/1-Benzoyl-4-(1-oxopropyl)-piperazine/1-(4-Benzoylpiperazin-1-yl)propan-1-one/1-Benzoyl-4-propanoylpiperazine/Sunifiram DM235
CAS No.: 314728-85-3
Molecular Formula: C14H18N2O2
Molecular Weight: 246.30492
Boiling Point: ° C at 760 mmHg
Storage Temp.: 2-8°C
Appearance: Off-white to white crystalline powder.
Product Categories: Intermediates&Fine Chemicals;Pharmaceuticals;Steroids
Sunifiram is one of the newest nootropics on the market to smart drugs family. It increases ones attention span, decision making, and learning abilities. Although its effect is believed to much like Piracetam, the structure is similar, it is more effective.
It is being researched as a memory enhancer, potentially treating Alzheimers patients. It provides a wide variety of benefits including; increased attention span, improved focus, and increased learning potential. It has become very popular since its release, as the benefits are high and the side-effects are low.
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