Doxorubicin Hydrochloride CAS 25316-40-9
Molecular Formula: C27H30ClNO11
Molecular Weight : 580.03
Melting Point: 216 °C (dec.)(lit.)
Boiling Point: 810.3 °C at 760 mmHg
Flash Point: 443.8 °C
Storage: Airtight container, protected from light
Appearance: Orange powder
It is a drug used in cancer chemotherapy. It is an anthracycline antibiotic, closely related to the natural product daunomycin, and like all anthracyclines, it works by intercalating DNA, with the most serious adverse effect being life-threatening heart damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.
1 Hodgkins disease and lymphosarcoma, reticulum cell sarcoma.
2 undifferentiated small cell and non-small cell lung cancer, breast cancer.
3 acute lymphoblastic and myeloid leukemia.
4 osteosarcoma and soft tissue sarcoma.
5 ovarian cancer, testicular cancer, bladder cancer, . Wilms cancer, prostate cancer, thyroid cancer, neuroblastoma cancer, esophageal cancer, stomach cancer, liver cancer, cervical cancer and head and neck cancer. Multiple myeloma, pancreatic cancer, endometrial cancer and brain tumors can also be applied.
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