99% Pure Idebenone Powder Idbn Nootropic CAS 58186-27-9 Stimulants Drugs
Cognition Enhancer 99% Idebenone Powder 58186-27-9 for Nootropic Drugs
Idebenone CAS No:58186-27-9
Idebenone Molecular formula:C19H30O5
Idebenone Molecular weight:338.44
Idebenone Assay:99% min pure
Idebenone Appearance: orange-yellow crystalline powder
Catalogue:Pharmaceutical materials;Health supplements;APIs;Brain health drug;Nootropic
Other Nootropics we offer:noopept;hydroxypiracetam;piracetam;Ferulic Acid;COLURACETAM
What is Idebenone
Idebenone (pronounced eye-deb-eh-known, trade names Catena, Raxone, Sovrima, among others) is a drug that was initially developed by Takeda Pharmaceutical Company for the treatment of Alzheimers disease and other cognitive defects.This has been met with limited success. The Swiss company Santhera Pharmaceuticals has started to investigate it for the treatment of neuromuscular diseases
Idebenone are used for:
Nootropic effects and Alzheimers disease
Idebenone improved learning and memory in experiments with mice.In humans, evaluation of Surrogate endpoints like electroretinography, auditory evoked potentials and visual analogue scales also suggested positive nootropic effects, but larger studies with hard endpoints are missing.
Friedreichs ataxia (Sovrima)
Preliminary testing has been done in humans and found idebenone to be a safe treatment for Friedreichs ataxia (FA), exhibiting a positive effect on cardiac hypertrophy and neurological function.The latter was only significantly improved in young patients. In a different experiment, a one-year test on eight patients, idebenone reduced the rate of deterioration of cardiac function, but without halting the progression of ataxia.
Other neuromuscular diseases
Phase I and II clinical trials for the treatment of MELAS (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) and primary progressive multiple sclerosis are ongoing as of December 2013.
Pharmacokinetics of Idebenone
Idebenone is well absorbed from the gut but undergoes excessive first pass metabolism in the liver, so that less than 1% reach the circulation. This rate can be improved with special formulations (suspensions) of idebenone and by administering it together with fat food; but even taking these measures bioavailability still seems to be considerably less than 14% in humans. More than 99% of the circulating drug are bound to plasma proteins. Idebenone metabolites include glucuronides and sulfates, which are mainly (~80%) excreted via the urine.
99% Pure Idebenone Powder Idbn Nootropic Raw Steroid Powders CAS 58186-27-9 Images