Local Anesthetic Dibucaine Hydrochloride For Pain Killer CAS: 61-12-1
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Dibucaine hydrochloride Desc.
Dibucaine Hydrochloride is a lactam anesthetics, local anesthetics in clinical application, cinchocaine is the strongest, the most toxic, their longest one. Anesthesia strength was 15 times the injection of procaine, toxicity 15 times. Slow onset, about 15min, but the duration of action is 3 times procaine. Local irritation, penetration is strong. For surface anesthesia, anesthesia or epidural anesthesia.
Dibucaine Hydrochloride Spec.
Name: Dibucaine Hydrochloride
CAS No.: 61-12-1
Molecular Weight: 379.98
Synonyms: 4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (9CI);Cinchoninamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (8CI);2-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;2-Butoxy-N-(2-diethylaminoethyl)cinchoninic acid amide hydrochloride;2-n-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;Benzolin (local anesthetic);Cincaine;Cincaine chloride;Cinchocainehydrochloride;Cinchocainium chloride;Nupercainehydrochloride;Percain;Percaine;Percamin S;Sovcain;Sovcaine;
Melting Point: 99-101 °C(lit.)
Boiling Point: 496.3 °C at 760 mmHg
Flash Point: 254 °C
Appearance: white powder
Hazard Symbols: HarmfulXn
Risk Codes: 22-41
Storage: Shading, confined preservation,
Cinchocaine (INN/BAN) or dibucaine (USAN) is an amide local anesthetic. Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia. It is sold under the brand names Cincain, Nupercainal, Nupercaine andSovcaine.
Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membranes permeability to sodium ions. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia.
(From Martindale, The Extra Pharmacopoeia, 30th ed, p1006) Indication: For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks. Dibucaine Hydrochloride is an amide-type local anesthetic, similar to lidocaine.
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