SARMs S4 / Andarine / GTX-007 Modest Strength And Muscle Gain / Fat loss CAS 401900-40-1
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CAS 401900-40-1 Andarine S-4
Andarine (GTx-007, S-4) is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy,using the non-steroidal androgen antagonist bicalutamide as a lead compound.
Andarine is an orally active partial agonist for androgen receptors. It is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH
S-4 belongs to a class of chemicals known as SARMS or selective androgen receptor modulators. Like typical androgens, SARMS bind to the androgen receptor however SARMS create selective anabolic activity.Compared to testosterone and other anabolic steroids and pro hormones, the advantage of SARMS such as S-4 is that they do not have androgenic activity in non-skeletal-muscle tissues.
Losing Bodyfat (Cutting)
Certain steroids are considered “cutting” steroids such as Winstrol and Anavar. These steroids don’t offer too much in large gains in muscle mass but are very effective in leaning out the body. The SARM S-4 has very similar properties.As S-4 shows this binding affinity to the AR, it demonstrates the similar fat burning effects. S-4 also shows a decrease in LPL (lipoprotein lipase) which is an enzyme that causes lipid accumulation.
S-4 also fits into a cutting protocol for the concurrent reduction in body fat with maintenance of muscle mass in a hypocaloric environment.
As S4 has both anabolic and androgenic effects in muscle tissue, it will not only help with fat loss, but maintain and even increase muscle mass when cutting.S-4 causes increases in vascularity and promote a very nice, “quality”, hard look to the users muscles, with little or no water retention.
In this way S-4 can be compared to Winstrol, without the harsh hair loss or extreme adverse effects on cholesterol.
Also other popular steroids/Prohormones used for cutting such as winstrol or epistane can have a notable effect on drying out of the joints. S-4 doesn’t suffer such consequences so the athlete is still able to lift heavy in order to maintain/increase muscle mass and strength.
Another advantage S-4 offers for cutting is that it doesn’t give the painful pumps associated with other popular steroids/Prohormones. Back and calf pumps are particularly detrimental for cutting as it limits the ability to perform cardio.
Strength gains and Lean mass Gains
Due to its androgenicity in muscle tissue, S-4 is a good agent for increases in strength without bloat and large increases in weight.Dosing at 50mg+ is the sweet spot for such gains.
Also, like the oral steroid Anavar (Var) weight gain with S4 may not be that great in comparison to bulking steroids such as deca or Superdrol, but what the lean mass and strength gained during the cycle is kept and not lost after the cycle.
With all dosing protocols, as the half life of S-4 is 4 hours, splitting up the dose into multiple applications is advised.
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|Enobosarm (Ostarine, MK-2866, GTx-024)
||partial agonist, intended mainly for treatment of benign prostatic hypertrophy
||a growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly
||pharmacological profile similar to that of enobosarm,
||It had been investigated as a potential treatment for obesity,diabetes,dyslipidemia and cardiovascular disease
||AICAR acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown
||developmental code name BIMT-17; that is being studied as a non-hormonal treatment for pre-menopausal women with HSDD.
||code name BCI-540; formerly MKC-231
||Pirespa, INN, BAN
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SARMs S4 / Andarine / GTX-007 Modest Strength And Muscle Gain / Fat loss CAS Images