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HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

HONGKONG XINCHENG GONGCHUANG TECHNOLOGY CO., LTD.

Home > Products > Testosterone Enanthate Powder > High Purity Clostebol is the 4-chloro derivative of the natural hormone
 

High Purity Clostebol is the 4-chloro derivative of the natural hormone

Place of Origin:
HUBEI,CHINA
Brand Name:
HKYC
Certification:
ISO 9000, SGS
Model Number:

566-48-3

Min.Order Quantity:
10grams
Price:
negotiable(best offer will be provided)
Packaging Details:
designed disguised packing ways, 100% pass custom guarantee)
Delivery Time:
within 24hours after payment confirm
Payment Terms:
MoneyGram, Western Union, T/T, Bitcoin
Supply Ability:
1000Kg per Month
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Product Description

4-Hydroxy Testosterone


Chemical Name: 4-Androsten-4,17beta-ol-3-one
CAS:566-48-3
Molecular Formula: C19H28O3
Molecular weight: 304.42
Standard: Enterprise Standard


Clostebol is the 4-chloro derivative of the natural hormone testosterone.

Product Name:4-Chlorotestosterone,Clostebol
CAS NO.:1093-58-9
EINECS:214-133-9
Molecular Formula:C19H27ClO2
Molecular Weight:322.87
Appearance:white crystalline powder


Usage:Used as roborant for premature,postoperation and deeline serve illness,also can be used for nephrosclerosis,osteoporosis,leukopenia caused by anticarcinogen,etc.

Clostebol,usually as the ester clostebol acetate or clostebol enanthate, is a synthetic anabolic androgenic steroid. Clostebol is the 4-chloro derivative of the natural hormone testosterone.

It is a weak anabolic steroid which was used by athletes from the German Democratic Republic (East Germany).[citation needed] It is a version of testosterone that is chlorinated so as to prevent conversion to dihydrotestosterone (DHT) while also rendering the chemical incapable of conversion to estrogen.

Chlorotestosterone is a very simple derivative of testosterone made by attaching a chlorine atom at the 4 position. This slight modification makes for a very different molecule than testosterone. Clostebol has a slightly lower binding affinity for the AR than testosterone and no binding to the PR or GR. The chlorine atom blocks the action of aromatase on this molecule. This means that chlorotestosterone cannot be converted to estrogen and is converted to a less potent DHT derivative1. Because testosterone is converted to DHT and estrogen to some degree and because DHT and estrogen are inactive in muscle tissue, you lose a good portion of activity when using testosterone. You also lose some of testosterone’s activity due to binding to SHBG. Chlorotestosterone binds much more weakly to SHBG than testosterone does. This makes clostebol a very good choice as an anabolic as can be seen from the anabolic to androgenic ratio. This steroid was marketed with an acetate ester requiring daily injections. It is surprising that chlorotestosterone is not used more often but this is probably due to the fact that this steroid does not offer instant gratification in the form of “bloat”. A longer ester would make this steroid much more attractive.

Andriol is a unique oral testosterone product, developed by the international drug firm Organon. One of the more recently developed anabolic steroids, Andriol first became available in the early 1980′s. This compound contains 40 mg of testosterone undecanoate, based in oil (oleic acid) and sealed inside a capsule. Subtracting the ester weight, this equates to a dosage of approximately 25mg of raw testosterone per cap. The design of this steroid is quite different from that of most oral steroids. Drugs administered orally generally enter the blood stream through the liver. When a steroid compound is given this way without some form of structural protection, it will be quickly broken down during the “first pass”. This process leaves very little steroid intact, basically deactivating the drug. Adding a methyl group (c-17 AA) to the structure is one way to protect it from this process, however stress is also placed on the liver as a result. In some instances this stress can lead to actual damage to liver tissues, so the designers of this steroid sought another way to protect the testosterone molecule. With Andriol, this was accomplished by making a form of testosterone that would be absorbed through the lymphatic system. This is due to its high fat solubility brought about by the ester, and its suspension in oil. Having the compound absorbed this way was thought to be very advantageous, as it allows the steroid to bypass the destructive first-pass through liver. This should permit the compound to enter the blood stream intact, without the need for a harsh chemical alteration. The ester breaks off once it is in circulation of course, yielding free active Pharmacokinetics of Oral Testosterone. In design this steroid appears to be undecanoate that of a completely liver safe and orally active form of testosterone.


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